Krause is a painter, collage artist, and printmaker who incorporates digital mixed media into her art. Her work is exhibited regularly in galleries and museums and featured in numerous current periodicals and books.
Krause is Professor Emeritus at Massachusetts College of Art where she founded the Computer Arts Center and a member of Digital Atelier®, an artists collaborative, with Bonny Lhotka and Karin Schminke. She is a frequent speaker at conferences and symposia and a consultant for manufacturers and distributors of products which may be used by fine artists.
In July 1997, Krause organized “Digital Atelier: A printmaking studio for the 21st century" at the Smithsonian American Art Museum and was an artist-in-residence there for 21 days. For that work she and her colleagues received a Smithsonian/Computerworld Technology in the Arts Award. That same year, she worked with a group of curators to help them envision the potential of digital printmaking in “Media for a New Millennium” a work-tank/think-shop organized by the Vinalhaven Graphic Arts Foundation.
In 2000, Krause received a Kodak Innovator Award and in June 2001, with Digital Atelier, she demonstrated digital printmaking techniques at the opening of the Brooklyn Museum of Art 27th Print National, Digital: Printmaking Now. In 2007, she was a Von Hess Visiting Artist at the University of the Arts in Philadelphia.